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I am a 63 year old male vaccinated with the Pfizer vaccine in March and April 2021 for my first two doses, boosted with the Moderna booster in November 2021, and a Covid infection in August 2022. I am ready for a bivalent booster now, and I should be able to get either Pfizer or Moderna equally easily. I have seen nothing to suggest a reason to favor one over the other. There is various information I can use as clues: preliminary data on antibody response, eventual reports on the efficacy of the Moderna monovalent vaccine compared to Pfizer, discussions on mixing and matching vaccines, dosing for the initial boosters and bivalent boosters, etc., but I don't know if these are relevant after the formulas were updated, and I do not have the expertise to make any reasonable assumptions or know if there is even enough data for anyone to reasonably speculate on this. What I would like to do is to try to make a decision that I'll have reason to believe is better than a coin flip given my age, sex, and vaccination and infection history. If there is absolutely no basis for any sort of guess or speculation I'll figuratively flip a coin, of course, but if there is enough informed speculation to even slightly favor one over the other, I may as well go with that. Is there anything at this time to suggest I might want to prefer one over the other?
I agree that you should proceed with obtaining your bivalent booster dose as quickly as possible. I personally have no preference for which (Moderna or Pfizer) booster dose to seek, and I personally selected the appointment that was earliest available at a convenient location.
